Voxel-MARS and CMARS: Methods for Early detection of Alzheimer's Disease by Classification of Structural Brain MRI

by: Gerhard-Wilhelm Weber and Dr. Alper Cevik

PRESENTATION OUTLINE

Introduction

- Motivation

- Objectives

Background

- Biomarkers

- MARS/CMARS

Methodology

- Data

- Methods

Performance

- Results

- Discussions

Conclusions

- Conclusions

- Future Outlook

DEFINITIONS

Alzheimer's Disease (AD)

- Most common neurodegenerative disease

- Most common cause of dementia

- Causes problems with memory, thinking and behavior, interferes with daily tasks, eventually leads to death

- Prevalence gets higher due to increasing life expectancy

Mild Cognitive Impairment (MCI)

- Cognitive impairments beyond the expected ones due to age and education

- Increasing risk of converting to AD (at a rate of approximately 10% to 15% per year according to Petersen et al., 2004)